Hollis E. Krug, MD - Minneapolis VA Health Care System
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Minneapolis VA Health Care System

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Hollis E. Krug, MD

Dr. Hollis Krug

Chief Rheumatology, Minneapolis VA Health Care System

Co-PI Rheumatology Research Lab, Minneapolis VA Health Care System

Associate Clinical Professor of Medicine, University of Minnesota

Telephone 612-467-4198

Email: hollis.krug@va.gov



  • BS, University of Nebraska
  • MD, University of Minnesota

Research Interests

  • Pain
  • Bone biology and ankylosis
  • Arthritis
  • Effects of TNF inhibition on metabolism

Selected Publications

  • Dorman CW, Krug HE, Frizelle SP, Funkenbusch S, Mahowald ML. A comparison of DigiGait™ and TreadScan™ imaging systems: assessment of pain using gait analysis in murine monoarthritis. Journal of Pain Research 2014:7 25–35, 2013.
  • Anderson, SR, Krug, HE, Dorman, C, Frizelle, SV, Mahowald, ML. Analgesic effects of intra-articular Botulinum Toxin Type B (BoNT /B) in a murine model of chronic degenerative knee arthritis pain. Journal of Pain Research 3:161-168, 2010.
  • Krug HE, Frizelle S, McGarraugh P, Mahowald ML. Pain Behavior Measures to Quantitate Joint Pain and Response to Neurotoxin Treatment in Murine Models of Arthritis. Pain Medicine. 10(7):1218-1228, 2009
  • Mahowald ML, Krug HE, Singh JA, Dykstra D. Intra-articular Botulinum Toxin Type A: A new approach to treat arthritis joint pain. Toxicon 54 (2009) 658–667.
  • Canales BK, Leonard SM, Singh JA, Orzano IM, Zimmermann B, Weiland D, Monga M, Krug HE. Spondyloarthropathy: An independent risk factor for kidney stones. Journal of Endourology. 20(8):542-546, 2006.
  • Krug, HE, Taurog, JD. HLA-B27 has no effect on the phenotypic expression of Progressive Ankylosis in ank/ank mice. Journal of Rheumatology 27(5):1257-1259, 2000.
  • Krug, HE, Mahowald, ML, Halverson, PB, Sallis, JD, Cheung, HS. Phosphocitrate prevents disease progression in Murine Progressive Ankylosis. Arth Rheum 36(11):1603-1611, 1993.
  • Johnson K, Goding J, van Etten D, Sali A, Hu S-I, Farley D, Krug H, Hessle L, Millàn JL, Terkeltaub R. Linked Deficiencies in Extracellular PPi and Osteopontin Medicate Pathologic Calcification Associated with Defective PC-1 and ANK Expression. J Bone and Mineral Research J Bone Miner Res 18 (6): 994-1004, 2003.